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Hyperkalemia, hyperphosphatemia, hyperuricemia, hypocalcemia, and decreased urine output may be indicative of methotrexate-induced tumor lysis syndrome tls .

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Drink plenty of fluids while taking this medication unless your doctor tells you otherwiseDoing so helps your kidneys to remove the drug from your body and avoid some of the side effects.

Methotrexate can be toxic to your organsand may lower your blood cell countsYour blood will need to be tested oftenand you may need an occasional liver biopsyYour cancer treatments may be delayed based on the results.

Lumpstumors/abnormal growthsmay very rarely appear during methotrexate useThe drug must be stopped and treatment may be neededTell your doctor right away if new lumps/growths occur.

Methotrexate is usually not taken every dayYou must use the correct dose for your conditionSome people have died after taking methotrexate every day by accident.

Methotrexate is used to treat certain types of cancer or to control severe psoriasis or rheumatoid arthritis that has not responded to other treatmentsIt may also be used to control juvenile rheumatoid arthritisMethotrexate belongs to a class of drugs known as antimetabolitesIt works by slowing or stopping the growth of cancer cells and suppressing the immune system.

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